OncoDB.HCC Expression View

Gene name : REG1A
Ensembl ID ENSG00000115386
Description Lithostathine 1 alpha precursor (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Islet of Langerhans regenerating protein) (REG) (Regenerating protein I alpha) (Islet cells regeneration factor) (ICRF). [Source:Uniprot/SWISSPROT;Acc:P05451]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
40 percent with 2 folds change ( 17 up and 1 down in 45 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR, QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 2 from 74201092 bp to 84204053 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 745343 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (2.73) HK3 (0.53) HK4 (-0.87) HK5 (4.20) HK7 (0.11) HK9 (-0.48) HK11 (0.00) HK12 (0.00) HK13 (0.00) HK14 (0.00) HK15 (0.00) HK16 (0.00) HK18 (2.71) HK19 (0.00) HK20 (0.36) HK21 (-0.17) HK22 (3.17) HK24 (-0.08) HK27 (3.53) HK28 (0.28) HK29 (0.52) HK31 (0.59) HK33 (0.00) HK36 (-0.54) HK37 (4.62) HK38 (4.89) HK39 (2.68) HK42 (0.64) HK46 (-0.24) HK47 (0.55) HK49 (0.17) HK62 (1.68) HK63 (0.23) HK64 (-0.09) HK67 (-0.33) HK84 (-0.34) HK85 (0.00) SF1 (1.98) SF12 (2.68) SF15 (4.15) SF17 (0.94) SF18 (0.00) SF21 (-0.75) SF22 (6.19) SF23 (0.70) SF32 (0.66) SF34 (-1.09) SF35 (5.68) SF3 (0.42) SF30 (6.21) HK2 (0.00) HK23 (-0.86) HK41 (-0.75) SF4 (0.69) SF8 (4.06) SF9 (1.58)