OncoDB.HCC Expression View

Gene name : FN1
Ensembl ID ENSG00000115414
Description Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG). [Source:Uniprot/SWISSPROT;Acc:P02751]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
36 percent with 2 folds change ( 13 up and 8 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Honda et al., Gastroenterology 120:955(2001)
up     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Proteomic Analysis - - Li et al., Mol Cell Proteomics 3:399 (2004)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 2 from 210933409 bp to 221009041 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 139009 -- IMAGE clone locate on exon ( tblastx )
840726 -- IMAGE clone locate on exon ( tblastx )
897531 -- IMAGE clone locate on exon ( tblastx )
1870935 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.60) HK1 (0.02) HK3 (1.29) HK4 (1.64) HK5 (-1.18) HK7 (0.52) HK9 (-0.56) HK11 (1.92) HK12 (0.71) HK13 (0.41) HK14 (0.96) HK15 (0.64) HK16 (-0.09) HK18 (0.89) HK19 (2.06) HK20 (0.81) HK21 (1.51) HK22 (1.77) HK24 (1.49) HK27 (1.15) HK28 (-0.21) HK29 (-1.32) HK31 (0.18) HK33 (-0.49) HK36 (0.21) HK37 (1.33) HK38 (0.48) HK39 (0.98) HK42 (0.17) HK46 (0.41) HK47 (3.02) HK49 (0.92) HK62 (-0.77) HK63 (0.47) HK64 (1.02) HK67 (0.44) HK84 (2.41) HK85 (0.82) SF1 (-1.46) SF12 (-0.44) SF15 (-0.61) SF17 (-1.98) SF18 (-0.73) SF21 (-1.89) SF22 (-1.59) SF23 (-0.70) SF32 (-0.64) SF34 (0.61) SF35 (0.89) SF3 (1.03) SF30 (0.90) HK2 (-0.49) HK23 (-0.06) HK41 (-1.16) SF4 (-0.03) SF8 (-0.73) SF9 (-1.28)