OncoDB.HCC Expression View

Gene name : RND3
Ensembl ID ENSG00000115963
Description Rho-related GTP-binding protein RhoE (Rho family GTPase 3) (Rnd3) (Rho8) (MemB protein). [Source:Uniprot/SWISSPROT;Acc:P61587]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
87 percent with 2 folds change ( 0 up and 50 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 2 from 146032955 bp to 156052426 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 415851 -- IMAGE clone locate on exon ( tblastx )
784593 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.27) HK1 (-2.30) HK3 (-2.42) HK4 (-1.25) HK5 (-2.22) HK7 (-1.54) HK9 (-2.30) HK11 (-2.02) HK12 (-1.82) HK13 (-1.67) HK14 (-2.29) HK15 (-1.25) HK16 (-1.41) HK18 (-2.11) HK19 (-1.13) HK20 (-2.73) HK21 (-0.17) HK22 (-1.15) HK24 (-1.98) HK27 (-2.49) HK28 (-2.41) HK29 (-0.59) HK31 (-3.09) HK33 (-0.51) HK36 (-1.83) HK37 (-2.93) HK38 (-1.34) HK39 (-1.77) HK42 (-1.66) HK46 (-1.55) HK47 (-1.37) HK49 (-1.04) HK62 (-0.86) HK63 (-2.46) HK64 (-1.63) HK67 (-1.92) HK84 (-2.99) HK85 (-2.05) SF1 (-2.13) SF12 (-2.65) SF15 (-1.50) SF17 (-1.29) SF18 (-2.40) SF21 (-0.13) SF22 (-2.43) SF23 (-1.28) SF32 (-1.08) SF34 (-2.48) SF35 (-2.63) SF3 (-0.01) SF30 (-3.01) HK2 (-1.18) HK23 (-3.53) HK41 (-2.81) SF4 (-1.40) SF8 (-0.64) SF9 (-1.33)