OncoDB.HCC Expression View

Gene name : CFHR3
Ensembl ID ENSG00000116785
Description Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16). [Source:Uniprot/SWISSPROT;Acc:Q02985]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
40 percent with 2 folds change ( 9 up and 14 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 1 from 190010566 bp to 200031160 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 84750 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.24) HK1 (-0.88) HK3 (-2.87) HK4 (0.60) HK5 (-0.48) HK7 (-0.62) HK9 (1.16) HK11 (-0.09) HK12 (-0.74) HK13 (-1.92) HK14 (-0.88) HK15 (-1.77) HK16 (0.06) HK18 (-0.91) HK19 (-0.52) HK20 (-0.43) HK21 (-1.41) HK22 (2.72) HK24 (0.01) HK27 (-1.47) HK28 (0.56) HK29 (0.53) HK31 (0.18) HK33 (0.47) HK36 (0.87) HK37 (-1.51) HK38 (3.27) HK39 (-0.90) HK42 (-1.30) HK46 (0.27) HK47 (-3.28) HK49 (1.10) HK62 (0.25) HK63 (-0.31) HK64 (-0.51) HK67 (-0.15) HK84 (-1.22) HK85 (1.44) SF1 (1.20) SF12 (-1.55) SF15 (1.56) SF17 (0.51) SF18 (-0.09) SF21 (0.33) SF22 (3.92) SF23 (-0.11) SF32 (0.16) SF34 (0.96) SF35 (-1.55) SF3 (-0.03) SF30 (1.91) HK2 (-2.44) HK23 (-1.87) HK41 (-0.45) SF4 (0.23) SF8 (-0.46) SF9 (-0.60)