OncoDB.HCC Expression View

Gene name : HAO2
Ensembl ID ENSG00000116882
Description Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long- chain L-2-hydroxy acid oxidase). [Source:Uniprot/SWISSPROT;Acc:Q9NYQ3]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
70 percent with 2 folds change ( 3 up and 31 down in 48 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 114712925 bp to 124738276 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1553568 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.68) HK3 (-2.08) HK4 (-3.49) HK5 (-2.90) HK7 (0.22) HK9 (0.00) HK11 (-2.02) HK12 (-1.34) HK13 (0.78) HK14 (-2.64) HK15 (-6.00) HK16 (0.72) HK18 (-1.35) HK19 (-2.74) HK20 (1.50) HK21 (-2.45) HK22 (1.00) HK24 (-1.71) HK27 (-2.42) HK28 (-1.73) HK29 (-0.91) HK31 (0.29) HK33 (-4.79) HK36 (-1.66) HK37 (-3.15) HK38 (-1.68) HK39 (1.79) HK42 (0.87) HK46 (0.00) HK47 (0.00) HK49 (0.00) HK62 (-1.86) HK63 (0.63) HK64 (-2.58) HK67 (-1.23) HK84 (0.00) HK85 (-0.46) SF1 (-0.91) SF12 (-5.38) SF15 (-3.01) SF17 (0.00) SF18 (-5.63) SF21 (0.13) SF22 (0.00) SF23 (0.00) SF32 (1.69) SF34 (0.00) SF35 (-2.34) SF3 (-2.90) SF30 (-4.41) HK2 (-4.42) HK23 (-1.79) HK41 (0.54) SF4 (-3.75) SF8 (0.29) SF9 (-6.53)