OncoDB.HCC Expression View

Gene name : APOA1
Ensembl ID ENSG00000118137
Description Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)]. [Source:Uniprot/SWISSPROT;Acc:P02647]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
66 percent with 2 folds change ( 2 up and 35 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 11 from 111211677 bp to 121213876 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 200263 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.49) HK1 (-1.56) HK3 (-2.57) HK4 (-0.14) HK5 (-2.41) HK7 (-2.75) HK9 (-0.94) HK11 (0.20) HK12 (-1.03) HK13 (1.00) HK14 (-2.71) HK15 (-1.65) HK16 (-0.57) HK18 (-2.41) HK19 (-0.75) HK20 (-1.59) HK21 (-1.60) HK22 (0.44) HK24 (-0.33) HK27 (-9.24) HK28 (0.28) HK29 (-0.07) HK31 (-1.09) HK33 (-0.72) HK36 (0.30) HK37 (-2.63) HK38 (-6.88) HK39 (-2.59) HK42 (-4.02) HK46 (-2.54) HK47 (-1.35) HK49 (-0.17) HK62 (-2.22) HK63 (-1.55) HK64 (-2.00) HK67 (0.54) HK84 (-2.55) HK85 (1.07) SF1 (-2.59) SF12 (-1.38) SF15 (-2.64) SF17 (-0.55) SF18 (0.00) SF21 (-0.85) SF22 (-1.60) SF23 (-0.21) SF32 (0.90) SF34 (0.44) SF35 (-4.96) SF3 (-1.52) SF30 (-6.89) HK2 (-1.01) HK23 (-1.64) HK41 (-2.76) SF4 (-2.77) SF8 (-0.98) SF9 (-1.85)