OncoDB.HCC Expression View

Gene name : ATF6
Ensembl ID ENSG00000118217
Description Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha). [Source:Uniprot/SWISSPROT;Acc:P18850]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
19 percent with 2 folds change ( 9 up and 2 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 1 from 155002708 bp to 165200484 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 417251 -- IMAGE clone locate on exon ( tblastx )
451711 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.56) HK1 (-0.16) HK3 (0.94) HK4 (0.88) HK5 (-0.98) HK7 (-0.49) HK9 (1.54) HK11 (0.68) HK12 (0.66) HK13 (1.33) HK14 (-0.24) HK15 (0.11) HK16 (-0.85) HK18 (-0.38) HK19 (-0.16) HK20 (0.03) HK21 (0.15) HK22 (0.08) HK24 (-0.06) HK27 (0.38) HK28 (-0.90) HK29 (-0.29) HK31 (0.80) HK33 (0.82) HK36 (0.49) HK37 (0.41) HK38 (1.51) HK39 (-0.26) HK42 (-0.41) HK46 (-0.54) HK47 (0.01) HK49 (0.26) HK62 (-0.63) HK63 (0.82) HK64 (0.93) HK67 (1.45) HK84 (0.07) HK85 (-1.12) SF1 (0.21) SF12 (0.22) SF15 (0.67) SF17 (1.95) SF18 (-0.18) SF21 (0.10) SF22 (-0.07) SF23 (0.89) SF32 (1.50) SF34 (-0.11) SF35 (-0.55) SF3 (-0.58) SF30 (-0.14) HK2 (0.23) HK23 (1.17) HK41 (1.69) SF4 (0.87) SF8 (0.99) SF9 (-1.01)