OncoDB.HCC Expression View

Gene name : TTR
Ensembl ID ENSG00000118271
Description Transthyretin precursor (Prealbumin) (TBPA) (TTR) (ATTR). [Source:Uniprot/SWISSPROT;Acc:P02766]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
58 percent with 2 folds change ( 7 up and 26 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 18 from 22425838 bp to 32432793 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 129589 -- IMAGE clone locate on exon ( blastn )
CH2 (-7.04) HK1 (-1.21) HK3 (-3.29) HK4 (1.48) HK5 (-0.98) HK7 (-0.49) HK9 (-1.20) HK11 (0.48) HK12 (-2.10) HK13 (1.05) HK14 (-2.33) HK15 (-2.82) HK16 (0.45) HK18 (-0.30) HK19 (-3.53) HK20 (-1.89) HK21 (-2.29) HK22 (0.66) HK24 (-0.27) HK27 (-1.38) HK28 (0.92) HK29 (0.32) HK31 (0.63) HK33 (0.54) HK36 (0.19) HK37 (-2.40) HK38 (-1.91) HK39 (-4.22) HK42 (-1.28) HK46 (-5.40) HK47 (0.00) HK49 (0.77) HK62 (0.17) HK63 (0.68) HK64 (-0.98) HK67 (-1.60) HK84 (-0.88) HK85 (1.26) SF1 (1.33) SF12 (-0.96) SF15 (-4.74) SF17 (0.32) SF18 (-1.72) SF21 (-0.28) SF22 (4.45) SF23 (-2.12) SF32 (2.83) SF34 (1.23) SF35 (-2.09) SF3 (-1.98) SF30 (-0.21) HK2 (-2.21) HK23 (-2.76) HK41 (0.89) SF4 (-2.35) SF8 (-2.08) SF9 (-0.61)