OncoDB.HCC Expression View

Gene name : ALDH8A1
Ensembl ID ENSG00000118514
Description aldehyde dehydrogenase 8A1 isoform 1 [Source:RefSeq_peptide;Acc:NP_072090]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
75 percent with 2 folds change ( 8 up and 34 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 6 from 130280222 bp to 140312946 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 294255 -- IMAGE clone locate on exon ( tblastx )
CH2 (-4.75) HK1 (-3.02) HK3 (-2.37) HK4 (-4.99) HK5 (0.00) HK7 (-3.22) HK9 (-2.40) HK11 (-2.16) HK12 (-1.24) HK13 (-2.77) HK14 (-3.05) HK15 (-5.55) HK16 (0.40) HK18 (-1.08) HK19 (-1.29) HK20 (-0.38) HK21 (-1.78) HK22 (1.15) HK24 (0.56) HK27 (-5.17) HK28 (-2.72) HK29 (-0.16) HK31 (0.87) HK33 (1.69) HK36 (-2.59) HK37 (-4.42) HK38 (-1.15) HK39 (-3.67) HK42 (-1.08) HK46 (-1.25) HK47 (-5.36) HK49 (-0.15) HK62 (-0.57) HK63 (-0.59) HK64 (-1.42) HK67 (1.02) HK84 (-2.62) HK85 (1.88) SF1 (-0.70) SF12 (-4.19) SF15 (-2.54) SF17 (-0.20) SF18 (-1.30) SF21 (3.92) SF22 (0.52) SF23 (1.66) SF32 (2.99) SF34 (2.06) SF35 (-3.14) SF3 (-4.83) SF30 (-4.61) HK2 (-2.60) HK23 (-1.60) HK41 (-0.06) SF4 (-0.45) SF8 (-0.84) SF9 (-4.82)