OncoDB.HCC Expression View

Gene name : NEK6
Ensembl ID ENSG00000119408
Description Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512). [Source:Uniprot/SWISSPROT;Acc:Q9HC98]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
20 percent with 2 folds change ( 2 up and 9 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR    
>> Link to terminologies used in OncoDB.HCC
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Display nearby genome region Chr 9 from 121059706 bp to 131155407 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 796876 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.11) HK1 (0.00) HK3 (-0.54) HK4 (0.19) HK5 (-0.60) HK7 (-1.09) HK9 (-1.33) HK11 (-0.15) HK12 (0.43) HK13 (-0.26) HK14 (0.39) HK15 (0.23) HK16 (0.20) HK18 (0.38) HK19 (0.04) HK20 (-0.49) HK21 (0.46) HK22 (-0.45) HK24 (-0.30) HK27 (-0.07) HK28 (-1.12) HK29 (-0.46) HK31 (-1.24) HK33 (-0.59) HK36 (0.06) HK37 (1.39) HK38 (-0.58) HK39 (0.30) HK42 (-0.43) HK46 (0.12) HK47 (1.20) HK49 (-0.82) HK62 (-1.36) HK63 (0.12) HK64 (0.26) HK67 (0.51) HK84 (0.00) HK85 (-1.54) SF1 (-1.06) SF12 (0.41) SF15 (-0.69) SF17 (-0.50) SF18 (0.13) SF21 (-1.34) SF22 (0.02) SF23 (-0.08) SF32 (-0.26) SF34 (-0.96) SF35 (-1.33) SF3 (0.24) SF30 (-0.11) HK2 (0.09) HK23 (-0.97) HK41 (-0.23) SF4 (-0.74) SF8 (-0.01) SF9 (-0.36)