OncoDB.HCC Expression View

Gene name : TEK
Ensembl ID ENSG00000120156
Description Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen). [Source:Uniprot/SWISSPROT;Acc:Q02763]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
51 percent with 2 folds change ( 0 up and 23 down in 45 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 9 from 22099236 bp to 32220173 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 151501 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-1.79) HK3 (-0.37) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-0.33) HK12 (-0.83) HK13 (-1.06) HK14 (-3.32) HK15 (-0.55) HK16 (0.08) HK18 (-1.75) HK19 (-1.07) HK20 (-0.70) HK21 (-1.31) HK22 (0.00) HK24 (-0.94) HK27 (-2.26) HK28 (-1.65) HK29 (-1.16) HK31 (-0.87) HK33 (-0.66) HK36 (-1.60) HK37 (0.00) HK38 (-2.50) HK39 (-1.99) HK42 (0.35) HK46 (-2.58) HK47 (0.00) HK49 (0.00) HK62 (-0.57) HK63 (-2.19) HK64 (-1.94) HK67 (0.00) HK84 (-1.48) HK85 (-0.67) SF1 (0.22) SF12 (-2.46) SF15 (-1.63) SF17 (0.07) SF18 (-1.95) SF21 (0.09) SF22 (0.00) SF23 (0.00) SF32 (-0.79) SF34 (-0.19) SF35 (-1.12) SF3 (-4.14) SF30 (0.00) HK2 (-1.00) HK23 (-0.68) HK41 (-0.44) SF4 (0.14) SF8 (-1.80) SF9 (-0.74)