OncoDB.HCC Expression View

Gene name : TNFSF11
Ensembl ID ENSG00000120659
Description Tumor necrosis factor ligand superfamily member 11 (Receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation- induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF) (CD254 antigen) [Source:Uniprot/SWISSPROT;Acc:O14788]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
44 percent with 2 folds change ( 3 up and 5 down in 18 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 13 from 37034872 bp to 47079308 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 825287 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.00) HK3 (-1.26) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.46) HK12 (0.00) HK13 (-0.99) HK14 (0.33) HK15 (-0.95) HK16 (0.00) HK18 (0.84) HK19 (0.00) HK20 (-2.00) HK21 (1.90) HK22 (-1.60) HK24 (1.13) HK27 (-2.82) HK28 (0.23) HK29 (0.00) HK31 (0.00) HK33 (1.85) HK36 (0.67) HK37 (0.00) HK38 (0.00) HK39 (0.00) HK42 (0.00) HK46 (-1.49) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (-0.04) SF34 (0.00) SF35 (0.00) SF3 (0.00) SF30 (0.00) HK2 (0.00) HK23 (0.98) HK41 (0.00) SF4 (0.00) SF8 (0.00) SF9 (0.00)