OncoDB.HCC Expression View

Gene name : EGR1
Ensembl ID ENSG00000120738
Description Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225). [Source:Uniprot/SWISSPROT;Acc:P18146]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
78 percent with 2 folds change ( 0 up and 37 down in 47 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 5 from 132829338 bp to 142831669 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 840944 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.34) HK1 (-1.58) HK3 (-3.20) HK4 (-2.60) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-1.04) HK12 (-0.28) HK13 (-3.37) HK14 (-1.21) HK15 (-2.22) HK16 (-1.98) HK18 (-2.55) HK19 (-0.48) HK20 (-2.43) HK21 (-0.15) HK22 (-1.80) HK24 (-2.63) HK27 (-0.99) HK28 (-1.97) HK29 (-0.03) HK31 (-3.81) HK33 (-0.63) HK36 (-0.19) HK37 (-3.01) HK38 (-3.14) HK39 (-1.17) HK42 (-2.26) HK46 (-1.12) HK47 (-3.64) HK49 (-0.24) HK62 (-2.03) HK63 (-2.53) HK64 (-5.65) HK67 (-2.26) HK84 (-3.40) HK85 (-0.76) SF1 (-4.48) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (-1.33) SF34 (0.08) SF35 (-3.64) SF3 (-3.01) SF30 (-1.88) HK2 (-2.57) HK23 (-2.39) HK41 (-1.85) SF4 (-1.01) SF8 (-1.31) SF9 (-1.48)