OncoDB.HCC Expression View

Gene name : TMPO
Ensembl ID ENSG00000120802
Description Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]. [Source:Uniprot/SWISSPROT;Acc:P42167]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
17 percent with 2 folds change ( 10 up and 0 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 12 from 92433527 bp to 102468250 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 79761 -- IMAGE clone locate on exon ( tblastx )
454083 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.44) HK1 (0.06) HK3 (1.11) HK4 (0.59) HK5 (-0.12) HK7 (-0.52) HK9 (1.34) HK11 (0.34) HK12 (-0.06) HK13 (1.20) HK14 (0.99) HK15 (-0.03) HK16 (-0.50) HK18 (-0.25) HK19 (0.81) HK20 (0.75) HK21 (-0.12) HK22 (-0.04) HK24 (0.73) HK27 (0.89) HK28 (-0.09) HK29 (0.60) HK31 (-0.12) HK33 (1.06) HK36 (0.55) HK37 (1.14) HK38 (0.61) HK39 (0.53) HK42 (1.93) HK46 (-0.07) HK47 (-0.48) HK49 (0.12) HK62 (0.47) HK63 (0.87) HK64 (0.70) HK67 (-0.25) HK84 (1.02) HK85 (1.44) SF1 (0.73) SF12 (0.83) SF15 (0.07) SF17 (0.41) SF18 (0.19) SF21 (-0.55) SF22 (0.27) SF23 (-0.02) SF32 (0.02) SF34 (0.89) SF35 (0.99) SF3 (0.24) SF30 (1.72) HK2 (-0.05) HK23 (0.03) HK41 (0.72) SF4 (0.02) SF8 (-0.02) SF9 (0.90)