OncoDB.HCC Expression View

Gene name : DDX3X
Ensembl ID ENSG00000124487
Description ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform). [Source:Uniprot/SWISSPROT;Acc:O00571]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
20 percent with 2 folds change ( 1 up and 10 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR, QPCR, IHC, Western    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr X from 36077595 bp to 46108669 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 745188 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.58) HK3 (-0.02) HK4 (0.00) HK5 (-1.25) HK7 (-0.72) HK9 (-0.53) HK11 (-0.20) HK12 (-0.43) HK13 (0.23) HK14 (-0.41) HK15 (-0.13) HK16 (-1.19) HK18 (-0.09) HK19 (-0.90) HK20 (0.05) HK21 (-0.07) HK22 (0.26) HK24 (-0.95) HK27 (-0.85) HK28 (-1.29) HK29 (-2.45) HK31 (-0.02) HK33 (-0.53) HK36 (-0.17) HK37 (0.00) HK38 (-0.08) HK39 (-0.21) HK42 (-0.90) HK46 (-0.96) HK47 (0.27) HK49 (0.40) HK62 (-2.21) HK63 (0.18) HK64 (0.55) HK67 (0.40) HK84 (-1.65) HK85 (-0.39) SF1 (-0.74) SF12 (-1.12) SF15 (1.57) SF17 (-0.23) SF18 (-0.19) SF21 (-0.24) SF22 (-1.71) SF23 (-0.88) SF32 (-0.80) SF34 (-1.39) SF35 (-1.30) SF3 (-0.52) SF30 (-0.02) HK2 (0.01) HK23 (-0.25) HK41 (-0.32) SF4 (-0.62) SF8 (0.44) SF9 (-0.50)