OncoDB.HCC Expression View

Gene name : DEK
Ensembl ID ENSG00000124795
Description Protein DEK. [Source:Uniprot/SWISSPROT;Acc:P35659]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 11 up and 5 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Northern, RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 6 from 13332392 bp to 23372750 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 133136 -- IMAGE clone locate on exon ( blastn )
46213 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.55) HK1 (-1.07) HK3 (1.43) HK4 (1.82) HK5 (-0.20) HK7 (0.56) HK9 (1.60) HK11 (0.81) HK12 (0.39) HK13 (2.02) HK14 (1.97) HK15 (-0.65) HK16 (-0.10) HK18 (0.15) HK19 (0.81) HK20 (0.58) HK21 (0.28) HK22 (0.51) HK24 (0.09) HK27 (1.03) HK28 (-0.52) HK29 (-1.50) HK31 (-0.11) HK33 (0.56) HK36 (-0.54) HK37 (0.94) HK38 (0.17) HK39 (0.96) HK42 (1.93) HK46 (0.43) HK47 (0.98) HK49 (0.33) HK62 (-0.15) HK63 (0.70) HK64 (0.28) HK67 (1.77) HK84 (0.00) HK85 (1.38) SF1 (0.55) SF12 (0.08) SF15 (0.42) SF17 (-1.10) SF18 (-1.81) SF21 (-1.23) SF22 (-0.26) SF23 (0.36) SF32 (-0.22) SF34 (0.02) SF35 (0.46) SF3 (-0.69) SF30 (1.95) HK2 (0.17) HK23 (0.77) HK41 (0.89) SF4 (-0.81) SF8 (0.16) SF9 (0.68)