OncoDB.HCC Expression View

Gene name : ID1
Ensembl ID ENSG00000125968
Description DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1). [Source:Uniprot/SWISSPROT;Acc:P41134]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
9 percent with 2 folds change ( 4 up and 1 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 20 from 24656747 bp to 34657979 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 810485 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.12) HK3 (0.26) HK4 (0.10) HK5 (-0.27) HK7 (-0.06) HK9 (-0.30) HK11 (0.39) HK12 (0.64) HK13 (0.14) HK14 (0.34) HK15 (0.06) HK16 (-1.45) HK18 (-0.46) HK19 (0.07) HK20 (0.86) HK21 (1.06) HK22 (-0.23) HK24 (0.56) HK27 (-0.49) HK28 (-0.08) HK29 (-0.87) HK31 (0.08) HK33 (0.08) HK36 (0.45) HK37 (0.49) HK38 (0.57) HK39 (-0.12) HK42 (-0.39) HK46 (-0.49) HK47 (-0.00) HK49 (0.61) HK62 (0.00) HK63 (-0.37) HK64 (1.20) HK67 (0.11) HK84 (0.06) HK85 (-0.26) SF1 (-0.45) SF12 (1.10) SF15 (1.28) SF17 (0.00) SF18 (0.27) SF21 (-0.40) SF22 (0.00) SF23 (-0.77) SF32 (0.51) SF34 (-0.26) SF35 (0.37) SF3 (0.04) SF30 (0.46) HK2 (-0.78) HK23 (0.70) HK41 (0.29) SF4 (0.56) SF8 (0.06) SF9 (-0.02)