OncoDB.HCC Expression View

Gene name : PROZ
Ensembl ID ENSG00000126231
Description Vitamin K-dependent protein Z precursor. [Source:Uniprot/SWISSPROT;Acc:P22891]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
77 percent with 2 folds change ( 5 up and 33 down in 49 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 13 from 107860969 bp to 114142980 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 430471 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.91) HK3 (-4.54) HK4 (-2.65) HK5 (3.47) HK7 (-2.86) HK9 (-1.43) HK11 (-2.84) HK12 (-3.33) HK13 (-0.80) HK14 (-2.91) HK15 (-3.75) HK16 (-2.32) HK18 (-3.03) HK19 (-1.33) HK20 (-0.77) HK21 (-2.57) HK22 (-0.60) HK24 (-2.40) HK27 (-5.03) HK28 (-1.54) HK29 (-2.87) HK31 (-0.51) HK33 (0.69) HK36 (-1.61) HK37 (0.00) HK38 (-2.56) HK39 (-3.29) HK42 (-0.75) HK46 (-2.44) HK47 (-3.63) HK49 (0.00) HK62 (0.91) HK63 (-1.97) HK64 (-0.76) HK67 (0.00) HK84 (0.00) HK85 (1.81) SF1 (0.50) SF12 (-3.76) SF15 (-2.10) SF17 (0.00) SF18 (0.00) SF21 (-1.04) SF22 (0.00) SF23 (2.55) SF32 (2.02) SF34 (0.25) SF35 (-2.31) SF3 (-3.53) SF30 (-2.85) HK2 (-3.93) HK23 (-1.44) HK41 (-2.24) SF4 (2.78) SF8 (-1.46) SF9 (-5.51)