OncoDB.HCC Expression View

Gene name : SGPP1
Ensembl ID ENSG00000126821
Description Sphingosine-1-phosphate phosphatase 1 (EC 3.1.3.-) (Sphingosine-1- phosphatase 1) (SPPase1) (Spp1) (hSPPase1). [Source:Uniprot/SWISSPROT;Acc:Q9BX95]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
45 percent with 2 folds change ( 0 up and 25 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 14 from 58220690 bp to 68264526 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 151850 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.84) HK1 (-0.17) HK3 (-0.39) HK4 (-0.03) HK5 (-1.41) HK7 (-0.03) HK9 (-1.45) HK11 (-0.82) HK12 (-0.95) HK13 (-1.15) HK14 (-1.45) HK15 (-0.81) HK16 (0.00) HK18 (-0.60) HK19 (-1.03) HK20 (-1.02) HK21 (0.44) HK22 (-0.86) HK24 (-0.96) HK27 (-1.27) HK28 (-0.40) HK29 (-0.97) HK31 (-1.18) HK33 (-1.44) HK36 (-1.11) HK37 (-0.05) HK38 (-0.08) HK39 (-0.81) HK42 (0.49) HK46 (-1.11) HK47 (-0.05) HK49 (-0.91) HK62 (-1.11) HK63 (-1.17) HK64 (-1.10) HK67 (0.12) HK84 (-1.85) HK85 (-1.10) SF1 (-0.07) SF12 (-1.31) SF15 (0.45) SF17 (-1.57) SF18 (-0.36) SF21 (-0.87) SF22 (-2.04) SF23 (-0.44) SF32 (0.00) SF34 (-1.04) SF35 (-1.30) SF3 (-1.04) SF30 (0.01) HK2 (-0.09) HK23 (-1.06) HK41 (-1.72) SF4 (-0.14) SF8 (-0.27) SF9 (-0.35)