OncoDB.HCC Expression View

Gene name : GNAI1
Ensembl ID ENSG00000127955
Description Guanine nucleotide-binding protein G(i), alpha-1 subunit (Adenylate cyclase-inhibiting G alpha protein). [Source:Uniprot/SWISSPROT;Acc:P63096]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
9 percent with 2 folds change ( 4 up and 1 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western, RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 7 from 74602076 bp to 84686655 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 753215 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.46) HK1 (0.64) HK3 (0.00) HK4 (-0.30) HK5 (0.25) HK7 (-0.17) HK9 (-0.26) HK11 (-0.65) HK12 (-0.08) HK13 (0.10) HK14 (-0.64) HK15 (0.21) HK16 (-1.05) HK18 (-0.68) HK19 (-0.59) HK20 (0.41) HK21 (0.75) HK22 (-0.13) HK24 (-0.00) HK27 (-0.55) HK28 (0.36) HK29 (0.52) HK31 (-0.58) HK33 (-0.17) HK36 (1.27) HK37 (-0.10) HK38 (-0.06) HK39 (0.38) HK42 (0.03) HK46 (0.80) HK47 (0.13) HK49 (0.05) HK62 (0.50) HK63 (0.70) HK64 (0.61) HK67 (0.90) HK84 (0.44) HK85 (0.85) SF1 (4.23) SF12 (0.55) SF15 (0.57) SF17 (1.15) SF18 (0.00) SF21 (0.19) SF22 (0.83) SF23 (0.00) SF32 (-0.08) SF34 (-0.12) SF35 (-0.81) SF3 (0.35) SF30 (-0.22) HK2 (0.66) HK23 (0.25) HK41 (1.08) SF4 (-0.12) SF8 (0.63) SF9 (0.25)