OncoDB.HCC Expression View

Gene name : TST
Ensembl ID ENSG00000128311
Description Thiosulfate sulfurtransferase (EC 2.8.1.1) (Rhodanese). [Source:Uniprot/SWISSPROT;Acc:Q16762]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
21 percent with 2 folds change ( 2 up and 10 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
up     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene    
Display nearby genome region Chr 22 from 30736853 bp to 40745437 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 784126 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.45) HK1 (-0.19) HK3 (-1.32) HK4 (0.84) HK5 (0.20) HK7 (0.52) HK9 (-0.51) HK11 (-0.71) HK12 (-1.04) HK13 (0.16) HK14 (0.10) HK15 (-1.28) HK16 (0.37) HK18 (-0.69) HK19 (-0.05) HK20 (-0.84) HK21 (-1.59) HK22 (0.34) HK24 (0.23) HK27 (-1.94) HK28 (0.29) HK29 (0.54) HK31 (0.08) HK33 (0.98) HK36 (0.36) HK37 (-0.86) HK38 (-0.62) HK39 (-0.69) HK42 (-1.42) HK46 (-0.42) HK47 (-2.98) HK49 (-0.73) HK62 (0.33) HK63 (-0.40) HK64 (0.19) HK67 (0.04) HK84 (-1.67) HK85 (1.52) SF1 (-0.90) SF12 (-0.56) SF15 (-0.95) SF17 (0.14) SF18 (-0.20) SF21 (0.02) SF22 (-0.48) SF23 (-0.54) SF32 (0.80) SF34 (1.33) SF35 (-0.97) SF3 (0.09) SF30 (-0.63) HK2 (-0.47) HK23 (-1.45) HK41 (-0.72) SF4 (0.16) SF8 (-0.51) SF9 (-1.91)