OncoDB.HCC Expression View

Gene name : IGLL1
Ensembl ID ENSG00000128322
Description Immunoglobulin lambda-like polypeptide 1 precursor (Immunoglobulin- related protein 14.1) (Immunoglobulin omega polypeptide) (Ig lambda-5) (CD179b antigen). [Source:Uniprot/SWISSPROT;Acc:P15814]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
71 percent with 2 folds change ( 7 up and 33 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 22 from 17245312 bp to 27252495 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 344134 -- IMAGE clone locate on exon ( tblastx )
CH2 (-3.57) HK1 (-4.67) HK3 (-0.44) HK4 (-2.84) HK5 (-4.34) HK7 (-0.55) HK9 (-2.50) HK11 (-0.14) HK12 (-1.09) HK13 (-2.72) HK14 (-4.04) HK15 (0.82) HK16 (1.81) HK18 (-0.27) HK19 (-0.87) HK20 (-3.14) HK21 (0.28) HK22 (-3.91) HK24 (-2.44) HK27 (-0.04) HK28 (-1.90) HK29 (-2.38) HK31 (-3.94) HK33 (-4.24) HK36 (-3.32) HK37 (-3.25) HK38 (-1.54) HK39 (1.65) HK42 (-3.54) HK46 (-0.61) HK47 (-2.94) HK49 (1.02) HK62 (2.19) HK63 (-2.98) HK64 (-1.93) HK67 (-0.90) HK84 (-0.37) HK85 (-1.46) SF1 (-2.04) SF12 (-2.48) SF15 (-3.39) SF17 (-5.24) SF18 (-1.53) SF21 (1.41) SF22 (1.83) SF23 (-0.77) SF32 (-2.73) SF34 (-0.49) SF35 (0.00) SF3 (0.24) SF30 (0.29) HK2 (-0.92) HK23 (-2.51) HK41 (-5.30) SF4 (-1.47) SF8 (-2.73) SF9 (1.84)