OncoDB.HCC Expression View

Gene name : BBOX1
Ensembl ID ENSG00000129151
Description Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine,2- oxoglutarate dioxygenase) (Gamma-butyrobetaine hydroxylase) (Gamma- BBH). [Source:Uniprot/SWISSPROT;Acc:O75936]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
90 percent with 2 folds change ( 6 up and 32 down in 42 paired-arrays )
With wet-lab experimental data from previous reports.
Links Entrez Gene    
Display nearby genome region Chr 11 from 22019574 bp to 32105930 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 812074 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-4.36) HK3 (-2.72) HK4 (0.00) HK5 (0.00) HK7 (-1.17) HK9 (0.00) HK11 (-3.09) HK12 (-1.70) HK13 (-4.15) HK14 (-4.87) HK15 (-4.02) HK16 (-0.26) HK18 (-0.57) HK19 (-1.02) HK20 (-1.11) HK21 (-3.65) HK22 (-3.33) HK24 (-3.57) HK27 (-3.46) HK28 (-1.23) HK29 (-1.96) HK31 (1.73) HK33 (0.28) HK36 (0.00) HK37 (-5.46) HK38 (-6.32) HK39 (-4.39) HK42 (2.45) HK46 (-6.49) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (1.28) HK64 (-0.97) HK67 (0.00) HK84 (0.00) HK85 (-2.27) SF1 (-1.64) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (1.15) SF22 (2.92) SF23 (0.00) SF32 (3.49) SF34 (-2.84) SF35 (-2.42) SF3 (-7.47) SF30 (-3.57) HK2 (-1.87) HK23 (-1.31) HK41 (-1.51) SF4 (-4.88) SF8 (-2.00) SF9 (-6.34)