OncoDB.HCC Expression View

Gene name : SHBG
Ensembl ID ENSG00000129214
Description Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG). [Source:Uniprot/SWISSPROT;Acc:P04278]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
70 percent with 2 folds change ( 3 up and 36 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 17 from 2472099 bp to 12477426 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 82871 -- IMAGE clone locate on exon ( blastn )
CH2 (-3.59) HK1 (-3.83) HK3 (-3.77) HK4 (-5.99) HK5 (-4.95) HK7 (-5.79) HK9 (0.35) HK11 (0.38) HK12 (-1.54) HK13 (-0.45) HK14 (-3.25) HK15 (-2.77) HK16 (-2.41) HK18 (-1.92) HK19 (-0.59) HK20 (-1.60) HK21 (-1.78) HK22 (-0.82) HK24 (-3.67) HK27 (-3.67) HK28 (-0.39) HK29 (-2.38) HK31 (-2.28) HK33 (1.97) HK36 (-2.70) HK37 (-0.39) HK38 (-1.50) HK39 (-2.69) HK42 (-3.56) HK46 (-0.85) HK47 (-1.81) HK49 (-2.11) HK62 (-3.37) HK63 (-1.44) HK64 (-3.16) HK67 (2.15) HK84 (0.00) HK85 (0.00) SF1 (-2.14) SF12 (-4.97) SF15 (-3.14) SF17 (0.94) SF18 (-3.23) SF21 (0.18) SF22 (-2.36) SF23 (-4.84) SF32 (2.41) SF34 (-0.09) SF35 (-2.30) SF3 (-0.21) SF30 (-2.10) HK2 (0.98) HK23 (0.12) HK41 (-2.37) SF4 (-0.87) SF8 (-0.29) SF9 (-1.99)