OncoDB.HCC Expression View

Gene name : CDKN1C
Ensembl ID ENSG00000129757
Description Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2). [Source:Uniprot/SWISSPROT;Acc:P49918]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
34 percent with 2 folds change ( 1 up and 10 down in 32 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- Western, SSCP    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 11 from 0 bp to 7863577 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 147744 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.45) HK3 (-0.48) HK4 (-3.03) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.35) HK12 (-0.79) HK13 (-0.34) HK14 (-0.65) HK15 (0.04) HK16 (0.00) HK18 (-0.75) HK19 (0.00) HK20 (-0.95) HK21 (0.00) HK22 (0.54) HK24 (-1.16) HK27 (-1.39) HK28 (-0.92) HK29 (-0.22) HK31 (-1.36) HK33 (0.55) HK36 (-0.66) HK37 (0.00) HK38 (-1.05) HK39 (0.05) HK42 (4.47) HK46 (0.00) HK47 (0.00) HK49 (0.00) HK62 (-0.50) HK63 (-0.96) HK64 (-3.03) HK67 (0.00) HK84 (0.00) HK85 (-2.44) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (-0.24) SF22 (0.00) SF23 (0.00) SF32 (-1.89) SF34 (-0.70) SF35 (0.63) SF3 (-0.94) SF30 (-1.14) HK2 (0.00) HK23 (0.00) HK41 (-3.03) SF4 (0.00) SF8 (0.00) SF9 (0.00)