OncoDB.HCC Expression View

Gene name : APOC4
Ensembl ID ENSG00000130207
Description Apolipoprotein C-IV precursor (Apo-CIV) (ApoC-IV). [Source:Uniprot/SWISSPROT;Acc:P55056]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
36 percent with 2 folds change ( 6 up and 15 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Iizuka et al., Oncogene 22:3007 (2003)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 19 from 45137335 bp to 55144660 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 85509 -- IMAGE clone locate on exon ( blastn )
809523 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.37) HK1 (-0.20) HK3 (-1.74) HK4 (-0.05) HK5 (-0.06) HK7 (-0.41) HK9 (-0.10) HK11 (0.68) HK12 (-1.11) HK13 (0.33) HK14 (-1.23) HK15 (-1.24) HK16 (0.27) HK18 (-0.80) HK19 (0.43) HK20 (-0.75) HK21 (-1.40) HK22 (1.85) HK24 (1.43) HK27 (-1.46) HK28 (0.95) HK29 (-0.34) HK31 (-0.11) HK33 (0.23) HK36 (0.95) HK37 (-0.60) HK38 (0.87) HK39 (-1.84) HK42 (-2.68) HK46 (-0.01) HK47 (-0.22) HK49 (1.86) HK62 (-1.20) HK63 (0.37) HK64 (-0.18) HK67 (0.17) HK84 (-0.78) HK85 (2.44) SF1 (0.77) SF12 (-2.73) SF15 (-0.73) SF17 (-0.22) SF18 (-0.31) SF21 (-0.72) SF22 (4.48) SF23 (-4.28) SF32 (-0.32) SF34 (2.62) SF35 (-1.68) SF3 (0.25) SF30 (-3.23) HK2 (-0.84) HK23 (-1.60) HK41 (-0.43) SF4 (0.55) SF8 (-1.00) SF9 (-1.65)