OncoDB.HCC Expression View

Gene name : APOC1
Ensembl ID ENSG00000130208
Description Apolipoprotein C-I precursor (Apo-CI) (ApoC-I). [Source:Uniprot/SWISSPROT;Acc:P02654]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
47 percent with 2 folds change ( 9 up and 18 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Iizuka et al., Oncogene 22:3007 (2003)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 19 from 45109419 bp to 55114423 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 1472689 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.74) HK1 (-0.36) HK3 (-2.22) HK4 (1.22) HK5 (-0.52) HK7 (-0.62) HK9 (0.44) HK11 (0.53) HK12 (-0.46) HK13 (2.34) HK14 (-1.89) HK15 (-0.71) HK16 (-1.42) HK18 (-0.58) HK19 (0.72) HK20 (-1.53) HK21 (-1.13) HK22 (0.92) HK24 (0.20) HK27 (-1.08) HK28 (0.61) HK29 (-0.93) HK31 (1.56) HK33 (2.96) HK36 (-0.46) HK37 (-0.83) HK38 (-0.20) HK39 (-0.77) HK42 (-2.77) HK46 (0.49) HK47 (-0.49) HK49 (1.35) HK62 (-1.48) HK63 (-0.46) HK64 (-0.49) HK67 (-0.49) HK84 (-1.72) HK85 (-0.67) SF1 (2.81) SF12 (-1.16) SF15 (-2.11) SF17 (0.14) SF18 (-1.27) SF21 (-0.61) SF22 (-0.16) SF23 (0.52) SF32 (1.40) SF34 (1.44) SF35 (-1.25) SF3 (1.59) SF30 (-1.18) HK2 (-0.97) HK23 (-2.73) HK41 (-1.44) SF4 (-0.35) SF8 (-1.53) SF9 (-0.92)