OncoDB.HCC Expression View

Gene name : DNMT1
Ensembl ID ENSG00000130816
Description DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI). [Source:Uniprot/SWISSPROT;Acc:P26358]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
13 percent with 2 folds change ( 0 up and 4 down in 30 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR, QPCR, IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 19 from 5105023 bp to 15166811 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 276547 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.00) HK3 (-0.35) HK4 (-0.99) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-0.52) HK12 (-0.03) HK13 (-1.29) HK14 (-0.85) HK15 (-0.20) HK16 (-0.54) HK18 (-1.40) HK19 (-0.69) HK20 (0.06) HK21 (-0.25) HK22 (-0.25) HK24 (0.00) HK27 (0.00) HK28 (0.00) HK29 (0.00) HK31 (0.00) HK33 (0.00) HK36 (-0.29) HK37 (0.00) HK38 (-1.17) HK39 (-0.65) HK42 (-1.31) HK46 (-0.61) HK47 (-0.37) HK49 (-0.61) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (-0.66) SF1 (0.55) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.00) SF34 (-0.80) SF35 (0.00) SF3 (-0.01) SF30 (-0.82) HK2 (0.52) HK23 (0.00) HK41 (-0.37) SF4 (0.01) SF8 (-0.72) SF9 (-0.88)