OncoDB.HCC Expression View

Gene name : RGN
Ensembl ID ENSG00000130988
Description Regucalcin (RC) (Senescence marker protein 30) (SMP-30). [Source:Uniprot/SWISSPROT;Acc:Q15493]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
38 percent with 2 folds change ( 2 up and 20 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Iizuka et al., Oncogene 22:3007 (2003)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Liang et al., Proteomics 5:2258 (2005)
down     Proteomic Analysis - - Blanc et al., Proteomics 5:37788 (2005)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr X from 41822698 bp to 51837653 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 45099 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.78) HK1 (-0.96) HK3 (-1.63) HK4 (-0.23) HK5 (-1.40) HK7 (0.09) HK9 (-0.03) HK11 (0.12) HK12 (-0.93) HK13 (-1.67) HK14 (-2.96) HK15 (-2.04) HK16 (-0.12) HK18 (-1.49) HK19 (-1.78) HK20 (0.21) HK21 (-1.62) HK22 (1.76) HK24 (0.18) HK27 (-2.96) HK28 (-1.12) HK29 (-1.11) HK31 (0.58) HK33 (0.67) HK36 (0.16) HK37 (-1.28) HK38 (-0.95) HK39 (-0.63) HK42 (-2.07) HK46 (-0.74) HK47 (-0.87) HK49 (-1.19) HK62 (0.04) HK63 (0.05) HK64 (-1.67) HK67 (-0.16) HK84 (-0.93) HK85 (1.02) SF1 (0.43) SF12 (-1.18) SF15 (-0.37) SF17 (0.12) SF18 (-1.39) SF21 (-0.14) SF22 (0.97) SF23 (-0.24) SF32 (0.17) SF34 (0.99) SF35 (-2.39) SF3 (-0.29) SF30 (-2.76) HK2 (-0.64) HK23 (-0.89) HK41 (-0.33) SF4 (-0.80) SF8 (-0.85) SF9 (-3.05)