OncoDB.HCC Expression View

Gene name : LGALS3
Ensembl ID ENSG00000131981
Description Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP). [Source:Uniprot/SWISSPROT;Acc:P17931]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
45 percent with 2 folds change ( 21 up and 5 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 14 from 49673452 bp to 59681879 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 855910 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.72) HK1 (-0.15) HK3 (1.45) HK4 (0.19) HK5 (-0.99) HK7 (0.36) HK9 (-0.41) HK11 (1.86) HK12 (0.97) HK13 (-1.26) HK14 (3.05) HK15 (-0.67) HK16 (0.70) HK18 (1.25) HK19 (1.38) HK20 (-0.88) HK21 (2.71) HK22 (0.20) HK24 (-0.33) HK27 (1.26) HK28 (-0.20) HK29 (0.56) HK31 (0.13) HK33 (0.45) HK36 (0.75) HK37 (0.19) HK38 (1.51) HK39 (2.88) HK42 (1.35) HK46 (-1.04) HK47 (1.45) HK49 (1.81) HK62 (0.60) HK63 (1.31) HK64 (-0.68) HK67 (0.06) HK84 (0.58) HK85 (-0.12) SF1 (1.97) SF12 (0.83) SF15 (0.80) SF17 (-2.86) SF18 (3.51) SF21 (1.17) SF22 (0.99) SF23 (-1.68) SF32 (2.16) SF34 (-0.06) SF35 (1.56) SF3 (-1.00) SF30 (0.70) HK2 (-0.28) HK23 (1.14) HK41 (0.74) SF4 (0.30) SF8 (1.69) SF9 (1.61)