OncoDB.HCC Expression View

Gene name : KRAS
Ensembl ID ENSG00000133703
Description GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras). [Source:Uniprot/SWISSPROT;Acc:P01116]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
10 percent with 2 folds change ( 3 up and 3 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence mutation     Method -- Mutation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 12 from 20249449 bp to 30295121 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 307553 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.79) HK1 (-0.38) HK3 (-0.44) HK4 (0.14) HK5 (-0.61) HK7 (-1.42) HK9 (-0.14) HK11 (0.39) HK12 (-0.28) HK13 (0.13) HK14 (0.00) HK15 (-0.96) HK16 (-0.50) HK18 (-0.33) HK19 (0.27) HK20 (0.31) HK21 (0.68) HK22 (0.17) HK24 (-0.23) HK27 (0.53) HK28 (-0.94) HK29 (0.10) HK31 (0.52) HK33 (-0.00) HK36 (-0.28) HK37 (-0.44) HK38 (-0.07) HK39 (-0.60) HK42 (-0.93) HK46 (-0.43) HK47 (0.37) HK49 (0.63) HK62 (0.35) HK63 (0.79) HK64 (-0.47) HK67 (-0.18) HK84 (-0.29) HK85 (-0.09) SF1 (-1.18) SF12 (1.00) SF15 (-0.87) SF17 (0.37) SF18 (-0.96) SF21 (0.12) SF22 (0.27) SF23 (0.24) SF32 (0.24) SF34 (0.45) SF35 (-1.69) SF3 (-0.13) SF30 (1.49) HK2 (-0.39) HK23 (-0.15) HK41 (0.70) SF4 (0.14) SF8 (0.20) SF9 (0.97)