OncoDB.HCC Expression View

Gene name : TMEM106C
Ensembl ID ENSG00000134291
Description Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer). [Source:Uniprot/SWISSPROT;Acc:Q9BVX2]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
79 percent with 2 folds change ( 42 up and 1 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 12 from 41643670 bp to 51648901 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 121251 -- IMAGE clone locate on exon ( tblastx )
CH2 (4.25) HK1 (0.49) HK3 (2.32) HK4 (0.00) HK5 (1.22) HK7 (2.99) HK9 (2.77) HK11 (-5.64) HK12 (1.19) HK13 (0.00) HK14 (0.00) HK15 (3.23) HK16 (0.00) HK18 (1.38) HK19 (1.73) HK20 (4.14) HK21 (0.85) HK22 (1.12) HK24 (2.35) HK27 (3.40) HK28 (1.44) HK29 (2.00) HK31 (3.34) HK33 (-0.86) HK36 (2.55) HK37 (2.61) HK38 (0.81) HK39 (2.60) HK42 (4.48) HK46 (2.67) HK47 (1.01) HK49 (1.23) HK62 (0.28) HK63 (3.41) HK64 (2.43) HK67 (1.44) HK84 (2.05) HK85 (2.58) SF1 (2.22) SF12 (3.95) SF15 (1.29) SF17 (0.66) SF18 (1.29) SF21 (0.48) SF22 (3.47) SF23 (-0.15) SF32 (1.02) SF34 (0.00) SF35 (4.10) SF3 (1.58) SF30 (1.33) HK2 (3.36) HK23 (1.51) HK41 (2.59) SF4 (0.73) SF8 (1.33) SF9 (2.33)