OncoDB.HCC Expression View

Gene name : PHC2
Ensembl ID ENSG00000134686
Description Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2). [Source:Uniprot/SWISSPROT;Acc:Q8IXK0]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
71 percent with 2 folds change ( 4 up and 36 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 28561814 bp to 38613781 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 898328 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.64) HK1 (-1.11) HK3 (-0.89) HK4 (-2.02) HK5 (-2.73) HK7 (-1.14) HK9 (-0.84) HK11 (0.24) HK12 (-1.31) HK13 (-0.94) HK14 (-1.82) HK15 (0.08) HK16 (1.83) HK18 (-0.25) HK19 (0.06) HK20 (-1.20) HK21 (0.45) HK22 (-2.08) HK24 (-1.50) HK27 (-1.62) HK28 (-2.14) HK29 (-1.70) HK31 (-2.40) HK33 (-3.49) HK36 (-1.73) HK37 (-1.02) HK38 (-1.26) HK39 (1.74) HK42 (-1.68) HK46 (-1.77) HK47 (-5.21) HK49 (0.58) HK62 (0.71) HK63 (-3.37) HK64 (-1.20) HK67 (-0.73) HK84 (-1.14) HK85 (-1.84) SF1 (-1.67) SF12 (-2.21) SF15 (-0.69) SF17 (-3.49) SF18 (-2.16) SF21 (1.64) SF22 (-5.47) SF23 (-2.43) SF32 (-3.02) SF34 (-0.41) SF35 (0.74) SF3 (-0.28) SF30 (0.86) HK2 (-1.44) HK23 (-1.42) HK41 (-3.02) SF4 (-1.03) SF8 (0.00) SF9 (1.40)