OncoDB.HCC Expression View

Gene name : SDS
Ensembl ID ENSG00000135094
Description L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase). [Source:Uniprot/SWISSPROT;Acc:P20132]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
76 percent with 2 folds change ( 14 up and 28 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 12 from 107314640 bp to 117326075 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 85202 -- IMAGE clone locate on exon ( tblastx )
CH2 (-2.10) HK1 (-2.25) HK3 (-4.51) HK4 (-8.25) HK5 (-1.35) HK7 (1.98) HK9 (-8.20) HK11 (-0.33) HK12 (-1.21) HK13 (1.87) HK14 (-4.55) HK15 (-0.12) HK16 (-2.41) HK18 (-0.39) HK19 (-1.74) HK20 (-1.58) HK21 (-1.51) HK22 (1.77) HK24 (0.56) HK27 (0.27) HK28 (1.56) HK29 (0.82) HK31 (1.21) HK33 (1.99) HK36 (-2.66) HK37 (0.00) HK38 (1.56) HK39 (-1.96) HK42 (-1.08) HK46 (-5.38) HK47 (0.00) HK49 (-2.74) HK62 (-0.33) HK63 (-0.90) HK64 (-2.73) HK67 (-2.73) HK84 (-2.29) HK85 (-0.53) SF1 (3.52) SF12 (-1.10) SF15 (-3.50) SF17 (-0.19) SF18 (2.95) SF21 (6.41) SF22 (5.54) SF23 (-2.06) SF32 (5.16) SF34 (0.74) SF35 (-1.24) SF3 (-2.23) SF30 (1.08) HK2 (-4.52) HK23 (-3.73) HK41 (1.93) SF4 (-0.62) SF8 (-0.40) SF9 (-4.67)