OncoDB.HCC Expression View

Gene name : GLUL
Ensembl ID ENSG00000135821
Description Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase) (GS). [Source:Uniprot/SWISSPROT;Acc:P15104]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
0 percent with 2 folds change ( 0 up and 0 down in 23 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC, RT-PCR, IHC, Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 1 from 175617462 bp to 185627964 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 47151 -- IMAGE clone locate on exon ( blastn )
CH2 (0.00) HK1 (0.89) HK3 (0.00) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (-0.01) HK12 (0.55) HK13 (-0.37) HK14 (0.44) HK15 (-0.77) HK16 (-0.52) HK18 (-0.15) HK19 (0.49) HK20 (-0.12) HK21 (0.00) HK22 (-0.90) HK24 (-0.65) HK27 (-0.42) HK28 (-0.24) HK29 (0.00) HK31 (0.21) HK33 (0.00) HK36 (0.00) HK37 (-0.16) HK38 (-0.04) HK39 (-0.24) HK42 (0.00) HK46 (0.42) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (-0.93) SF34 (0.00) SF35 (0.00) SF3 (-0.23) SF30 (0.00) HK2 (0.00) HK23 (0.00) HK41 (0.00) SF4 (0.05) SF8 (0.00) SF9 (-0.65)