OncoDB.HCC Expression View

Gene name : SPRY2
Ensembl ID ENSG00000136158
Description Sprouty homolog 2 (Spry-2). [Source:Uniprot/SWISSPROT;Acc:O43597]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
54 percent with 2 folds change ( 0 up and 30 down in 55 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence down     Method -- QPCR, ISH, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 13 from 74808112 bp to 84813918 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 813698 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.60) HK1 (-0.37) HK3 (-2.07) HK4 (-1.56) HK5 (-1.57) HK7 (-0.24) HK9 (-1.50) HK11 (-0.68) HK12 (-0.24) HK13 (-0.24) HK14 (0.38) HK15 (-2.35) HK16 (-0.79) HK18 (-1.93) HK19 (-1.29) HK20 (-2.80) HK21 (-0.61) HK22 (-1.35) HK24 (-0.76) HK27 (-1.55) HK28 (-1.75) HK29 (-1.75) HK31 (-0.93) HK33 (-0.56) HK36 (-0.74) HK37 (-1.16) HK38 (-0.00) HK39 (-0.98) HK42 (-0.20) HK46 (-1.66) HK47 (0.00) HK49 (0.06) HK62 (-0.79) HK63 (-2.91) HK64 (-2.17) HK67 (-0.40) HK84 (0.00) HK85 (-1.70) SF1 (-2.15) SF12 (-2.42) SF15 (-0.10) SF17 (-1.96) SF18 (-1.00) SF21 (-1.80) SF22 (-1.84) SF23 (0.03) SF32 (-0.82) SF34 (-0.95) SF35 (-1.92) SF3 (-1.75) SF30 (-0.96) HK2 (-1.83) HK23 (-1.67) HK41 (-1.87) SF4 (-1.53) SF8 (-0.84) SF9 (-0.35)