OncoDB.HCC Expression View

Gene name : CYP1A1
Ensembl ID ENSG00000140465
Description Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1) (P450 form 6) (P450-C). [Source:Uniprot/SWISSPROT;Acc:P04798]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
77 percent with 2 folds change ( 5 up and 30 down in 45 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
Links Entrez Gene    
Display nearby genome region Chr 15 from 67798943 bp to 77802491 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 768064 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.85) HK3 (-3.60) HK4 (-0.42) HK5 (1.24) HK7 (0.00) HK9 (0.00) HK11 (-5.93) HK12 (-1.14) HK13 (-2.18) HK14 (-6.39) HK15 (-3.41) HK16 (0.86) HK18 (-1.88) HK19 (-2.48) HK20 (-0.75) HK21 (-3.58) HK22 (-2.09) HK24 (-2.23) HK27 (-3.26) HK28 (-3.99) HK29 (-0.91) HK31 (-1.26) HK33 (-3.53) HK36 (0.14) HK37 (-6.19) HK38 (-3.39) HK39 (-3.92) HK42 (0.00) HK46 (5.11) HK47 (0.00) HK49 (0.00) HK62 (-2.49) HK63 (0.00) HK64 (0.00) HK67 (-0.71) HK84 (0.00) HK85 (-2.90) SF1 (-4.31) SF12 (0.00) SF15 (0.00) SF17 (2.61) SF18 (0.00) SF21 (-3.34) SF22 (0.22) SF23 (-0.56) SF32 (-3.69) SF34 (-2.96) SF35 (-4.11) SF3 (-2.84) SF30 (-2.84) HK2 (0.17) HK23 (-1.71) HK41 (5.17) SF4 (-4.81) SF8 (1.35) SF9 (-5.01)