OncoDB.HCC Expression View

Gene name : SOD1
Ensembl ID ENSG00000142168
Description Superoxide dismutase [Cu-Zn] (EC 1.15.1.1). [Source:Uniprot/SWISSPROT;Acc:P00441]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
21 percent with 2 folds change ( 3 up and 9 down in 56 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
down     Proteomic Analysis - - Kim et al., Clin Cancer Research 9:5493 (2003)
down     Proteomic Analysis - - Li et al., Proteomics 5:1125 (2005)
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 21 from 26953954 bp to 36963001 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 950489 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.17) HK1 (-0.73) HK3 (0.35) HK4 (0.85) HK5 (-0.37) HK7 (-0.69) HK9 (-0.08) HK11 (-1.10) HK12 (-1.22) HK13 (0.53) HK14 (-0.25) HK15 (0.29) HK16 (0.39) HK18 (0.11) HK19 (-0.86) HK20 (-1.01) HK21 (-0.60) HK22 (-0.07) HK24 (-0.02) HK27 (0.69) HK28 (0.82) HK29 (-0.24) HK31 (0.97) HK33 (1.43) HK36 (-0.01) HK37 (0.87) HK38 (0.92) HK39 (-0.40) HK42 (-0.53) HK46 (-0.14) HK47 (1.77) HK49 (-1.29) HK62 (-0.14) HK63 (-0.80) HK64 (-0.01) HK67 (-0.45) HK84 (0.00) HK85 (-0.56) SF1 (1.13) SF12 (-1.40) SF15 (-0.85) SF17 (-0.57) SF18 (-1.01) SF21 (-1.73) SF22 (0.26) SF23 (0.37) SF32 (-0.81) SF34 (-0.20) SF35 (-0.20) SF3 (-0.09) SF30 (-0.20) HK2 (-0.36) HK23 (-0.23) HK41 (0.67) SF4 (-0.55) SF8 (-0.74) SF9 (-1.65)