OncoDB.HCC Expression View

Gene name : BCL10
Ensembl ID ENSG00000142867
Description B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (CARD- containing molecule enhancing NF-kappa-B) (Cellular homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecu [Source:Uniprot/SWISSPROT;Acc:O95999]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
15 percent with 2 folds change ( 6 up and 2 down in 53 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence mutation     Method -- Mutation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 1 from 80504519 bp to 90516359 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 812172 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.26) HK3 (0.57) HK4 (0.69) HK5 (-0.08) HK7 (0.31) HK9 (-0.28) HK11 (0.33) HK12 (-0.02) HK13 (0.49) HK14 (-0.09) HK15 (1.50) HK16 (1.92) HK18 (0.50) HK19 (-0.55) HK20 (0.89) HK21 (0.51) HK22 (0.37) HK24 (0.35) HK27 (-0.47) HK28 (-0.32) HK29 (0.19) HK31 (0.43) HK33 (-0.09) HK36 (-0.35) HK37 (1.02) HK38 (0.43) HK39 (-0.09) HK42 (0.79) HK46 (0.37) HK47 (0.00) HK49 (0.05) HK62 (-1.94) HK63 (1.12) HK64 (1.09) HK67 (0.00) HK84 (0.96) HK85 (0.53) SF1 (0.09) SF12 (2.09) SF15 (0.68) SF17 (-0.20) SF18 (-0.57) SF21 (-0.44) SF22 (0.29) SF23 (-0.33) SF32 (0.13) SF34 (-1.09) SF35 (0.16) SF3 (0.00) SF30 (0.88) HK2 (-0.21) HK23 (-0.58) HK41 (0.22) SF4 (-0.41) SF8 (0.40) SF9 (0.22)