OncoDB.HCC Expression View

Gene name : HDGF
Ensembl ID ENSG00000143321
Description Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2). [Source:Uniprot/SWISSPROT;Acc:P51858]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
14 percent with 2 folds change ( 8 up and 0 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC, RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA microarray - - Shirota et al., Hepatology 33:832 (2001)
up     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
Links Entrez Gene    
Display nearby genome region Chr 1 from 149978523 bp to 159988864 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 813673 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.09) HK1 (0.79) HK3 (0.71) HK4 (1.18) HK5 (0.88) HK7 (-0.50) HK9 (-0.14) HK11 (0.97) HK12 (0.33) HK13 (0.12) HK14 (0.75) HK15 (1.25) HK16 (0.22) HK18 (0.09) HK19 (0.91) HK20 (-0.15) HK21 (0.73) HK22 (0.23) HK24 (0.66) HK27 (0.85) HK28 (0.06) HK29 (0.27) HK31 (0.12) HK33 (1.70) HK36 (0.23) HK37 (0.24) HK38 (0.48) HK39 (0.63) HK42 (0.83) HK46 (1.01) HK47 (0.77) HK49 (0.55) HK62 (0.95) HK63 (0.63) HK64 (0.17) HK67 (0.31) HK84 (0.70) HK85 (0.79) SF1 (0.04) SF12 (-0.15) SF15 (-0.28) SF17 (0.88) SF18 (1.33) SF21 (0.61) SF22 (0.56) SF23 (-0.05) SF32 (0.09) SF34 (1.04) SF35 (0.45) SF3 (-0.23) SF30 (1.80) HK2 (0.89) HK23 (0.45) HK41 (0.62) SF4 (0.45) SF8 (0.07) SF9 (0.13)