OncoDB.HCC Expression View

Gene name : SNX27
Ensembl ID ENSG00000143376
Description Sorting nexin-27. [Source:Uniprot/SWISSPROT;Acc:Q96L92]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
49 percent with 2 folds change ( 28 up and 0 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 1 from 144851182 bp to 154938191 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 258279 -- IMAGE clone locate on exon ( tblastx )
773509 -- IMAGE clone locate on exon ( tblastx )
784258 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.18) HK1 (1.36) HK3 (1.65) HK4 (1.58) HK5 (1.26) HK7 (0.22) HK9 (1.44) HK11 (1.04) HK12 (0.68) HK13 (0.08) HK14 (1.14) HK15 (1.10) HK16 (0.24) HK18 (0.57) HK19 (1.23) HK20 (1.03) HK21 (0.53) HK22 (0.72) HK24 (0.84) HK27 (2.01) HK28 (0.62) HK29 (1.01) HK31 (1.09) HK33 (0.51) HK36 (0.16) HK37 (0.82) HK38 (1.58) HK39 (1.09) HK42 (1.71) HK46 (1.07) HK47 (1.84) HK49 (0.86) HK62 (1.04) HK63 (0.61) HK64 (1.18) HK67 (0.18) HK84 (1.30) HK85 (1.25) SF1 (1.43) SF12 (0.98) SF15 (0.95) SF17 (0.81) SF18 (2.06) SF21 (-0.59) SF22 (1.29) SF23 (-0.12) SF32 (0.17) SF34 (0.60) SF35 (0.84) SF3 (0.97) SF30 (2.60) HK2 (1.36) HK23 (0.94) HK41 (0.64) SF4 (0.61) SF8 (0.64) SF9 (0.35)