OncoDB.HCC Expression View

Gene name : PARP1
Ensembl ID ENSG00000143799
Description Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1). [Source:Uniprot/SWISSPROT;Acc:P09874]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     cDNA Microarray - - Neo et al., Hepatology 39:944 (2004)
up     Affy. Microarray - - Iizuka et al., J Cancer Res Clin Oncol 132:473 (2006)
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 1 from 219615015 bp to 229662414 bp