OncoDB.HCC Expression View

Gene name : RHOB
Ensembl ID ENSG00000143878
Description Rho-related GTP-binding protein RhoB precursor (H6). [Source:Uniprot/SWISSPROT;Acc:P62745]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 0 up and 16 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
down     cDNA Microarray - - Honda et al., Gastroenterology 120:955(2001)
down     EST and cDNA Microarray - - Xu et al., PNAS 98:15089 (2001)
down     cDNA Microarray - - Delpuech et al., Oncogene 21:2926 (2002)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     Entrez Gene     COSMIC    
Display nearby genome region Chr 2 from 15510316 bp to 25512687 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 277305 -- IMAGE clone locate on exon ( blastn )
253141 -- IMAGE clone locate on exon ( tblastx )
768370 -- IMAGE clone locate on exon ( tblastx )
1492448 -- IMAGE clone locate on exon ( tblastx )
CH2 (-0.90) HK1 (0.03) HK3 (-0.39) HK4 (-1.62) HK5 (-0.72) HK7 (-0.39) HK9 (-0.67) HK11 (-0.93) HK12 (-0.92) HK13 (0.12) HK14 (-2.09) HK15 (-0.20) HK16 (-0.67) HK18 (0.12) HK19 (-0.16) HK20 (-0.78) HK21 (-0.31) HK22 (-0.04) HK24 (-0.62) HK27 (-0.93) HK28 (0.43) HK29 (0.47) HK31 (-0.89) HK33 (0.14) HK36 (0.84) HK37 (-0.73) HK38 (-1.22) HK39 (-0.47) HK42 (-2.10) HK46 (-0.33) HK47 (-0.26) HK49 (0.86) HK62 (-0.59) HK63 (-3.02) HK64 (-0.82) HK67 (-0.58) HK84 (-1.62) HK85 (0.43) SF1 (-0.69) SF12 (-2.13) SF15 (-1.40) SF17 (-1.67) SF18 (-2.44) SF21 (-0.41) SF22 (-1.39) SF23 (-0.08) SF32 (-0.81) SF34 (-0.27) SF35 (-2.58) SF3 (-0.07) SF30 (-1.85) HK2 (0.22) HK23 (-1.83) HK41 (-0.04) SF4 (-1.64) SF8 (0.22) SF9 (-1.24)