OncoDB.HCC Expression View

Gene name : CCNA2
Ensembl ID ENSG00000145386
Description Cyclin-A2 (Cyclin-A). [Source:Uniprot/SWISSPROT;Acc:P20248]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
55 percent with 2 folds change ( 23 up and 7 down in 54 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- Western, IHC    
>> Link to terminologies used in OncoDB.HCC
Reference expression data
up     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene     COSMIC    
Display nearby genome region Chr 4 from 117958002 bp to 127964505 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 950690 -- IMAGE clone locate on exon ( tblastx )
CH2 (4.25) HK1 (0.93) HK3 (1.68) HK4 (0.18) HK5 (1.10) HK7 (1.61) HK9 (1.93) HK11 (0.20) HK12 (-0.14) HK13 (0.70) HK14 (0.98) HK15 (-2.28) HK16 (0.82) HK18 (0.52) HK19 (2.24) HK20 (-0.39) HK21 (1.18) HK22 (0.79) HK24 (0.42) HK27 (1.17) HK28 (-1.05) HK29 (1.14) HK31 (0.01) HK33 (0.00) HK36 (1.04) HK37 (1.64) HK38 (0.52) HK39 (3.80) HK42 (-0.11) HK46 (1.15) HK47 (1.03) HK49 (0.87) HK62 (2.65) HK63 (2.02) HK64 (4.76) HK67 (0.00) HK84 (0.00) HK85 (-3.84) SF1 (3.16) SF12 (2.91) SF15 (-1.15) SF17 (0.00) SF18 (0.00) SF21 (-6.12) SF22 (-6.00) SF23 (-0.36) SF32 (-0.58) SF34 (2.01) SF35 (0.56) SF3 (2.73) SF30 (2.42) HK2 (-1.11) HK23 (0.00) HK41 (1.33) SF4 (0.16) SF8 (0.10) SF9 (0.85)