OncoDB.HCC Expression View

Gene name : CDKN2B
Ensembl ID ENSG00000147883
Description Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2). [Source:Uniprot/SWISSPROT;Acc:P42772]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
30 percent with 2 folds change ( 2 up and 2 down in 13 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR, Methylation    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 9 from 16992902 bp to 26999312 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 277196 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (0.00) HK3 (-2.07) HK4 (0.00) HK5 (0.00) HK7 (0.00) HK9 (0.00) HK11 (0.00) HK12 (0.00) HK13 (-0.20) HK14 (-0.88) HK15 (0.00) HK16 (0.00) HK18 (0.00) HK19 (0.00) HK20 (0.00) HK21 (0.00) HK22 (0.00) HK24 (0.97) HK27 (0.00) HK28 (0.79) HK29 (0.00) HK31 (0.00) HK33 (0.00) HK36 (0.00) HK37 (0.00) HK38 (0.00) HK39 (0.00) HK42 (0.00) HK46 (0.00) HK47 (1.76) HK49 (1.69) HK62 (0.11) HK63 (0.02) HK64 (0.00) HK67 (0.00) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (0.00) SF21 (0.00) SF22 (0.00) SF23 (0.00) SF32 (0.00) SF34 (0.15) SF35 (0.00) SF3 (-2.17) SF30 (0.00) HK2 (0.00) HK23 (0.00) HK41 (0.00) SF4 (0.10) SF8 (-0.28) SF9 (0.00)