OncoDB.HCC Expression View

Gene name : TCF7L2
Ensembl ID ENSG00000148737
Description Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4). [Source:Uniprot/SWISSPROT;Acc:Q9NQB0]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
10 percent with 2 folds change ( 0 up and 6 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR, RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 10 from 109700201 bp to 119917427 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 366848 -- IMAGE clone locate on exon ( tblastx )
752652 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.43) HK1 (-0.26) HK3 (-0.37) HK4 (-1.01) HK5 (0.07) HK7 (-0.40) HK9 (-0.33) HK11 (-0.13) HK12 (-0.10) HK13 (-0.58) HK14 (0.09) HK15 (-0.57) HK16 (-0.54) HK18 (-0.93) HK19 (-0.09) HK20 (-0.50) HK21 (-0.31) HK22 (-0.53) HK24 (-0.48) HK27 (-0.60) HK28 (-1.23) HK29 (-0.10) HK31 (0.48) HK33 (-0.08) HK36 (0.10) HK37 (-0.48) HK38 (0.55) HK39 (-0.85) HK42 (0.21) HK46 (-0.72) HK47 (-0.32) HK49 (0.26) HK62 (-0.49) HK63 (-0.04) HK64 (-1.65) HK67 (-0.12) HK84 (-0.02) HK85 (-0.98) SF1 (-1.19) SF12 (-0.33) SF15 (0.15) SF17 (0.42) SF18 (0.41) SF21 (0.24) SF22 (0.07) SF23 (-0.77) SF32 (-1.12) SF34 (0.78) SF35 (-1.17) SF3 (-0.06) SF30 (0.18) HK2 (0.77) HK23 (-0.55) HK41 (-0.24) SF4 (-0.33) SF8 (0.17) SF9 (0.28)