OncoDB.HCC Expression View

Gene name : MKI67
Ensembl ID ENSG00000148773
Description Antigen KI-67. [Source:Uniprot/SWISSPROT;Acc:P46013]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
28 percent with 2 folds change ( 10 up and 5 down in 52 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- QPCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene     Entrez Gene     Entrez Gene    
Display nearby genome region Chr 10 from 124784913 bp to 134814639 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 510228 -- IMAGE clone locate on exon ( tblastx )
769513 -- IMAGE clone locate on exon ( tblastx )
CH2 (0.00) HK1 (-0.82) HK3 (-1.25) HK4 (4.92) HK5 (-0.35) HK7 (0.00) HK9 (1.29) HK11 (0.00) HK12 (-0.27) HK13 (0.00) HK14 (-0.81) HK15 (0.05) HK16 (3.57) HK18 (-0.91) HK19 (-0.08) HK20 (0.52) HK21 (-2.07) HK22 (-0.50) HK24 (-0.85) HK27 (-0.29) HK28 (-0.26) HK29 (0.65) HK31 (-1.02) HK33 (0.76) HK36 (0.32) HK37 (-0.49) HK38 (0.07) HK39 (0.47) HK42 (0.84) HK46 (-0.60) HK47 (-0.58) HK49 (-1.12) HK62 (1.34) HK63 (1.49) HK64 (-0.15) HK67 (-2.04) HK84 (0.75) HK85 (0.40) SF1 (-0.81) SF12 (1.97) SF15 (0.47) SF17 (3.07) SF18 (3.31) SF21 (4.63) SF22 (4.50) SF23 (0.00) SF32 (0.96) SF34 (-0.14) SF35 (0.61) SF3 (0.00) SF30 (0.83) HK2 (0.01) HK23 (-0.67) HK41 (0.12) SF4 (-0.80) SF8 (0.27) SF9 (0.67)