OncoDB.HCC Expression View

Gene name : SERPING1
Ensembl ID ENSG00000149131
Description Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor). [Source:Uniprot/SWISSPROT;Acc:P05155]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
40 percent with 2 folds change ( 6 up and 17 down in 57 paired-arrays )
With wet-lab experimental data from previous reports.
Reference expression data
up     cDNA Microarray - - Okabe et al., Cancer Res. 61:2129 (2001)
down     cDNA Microarray - - Xu et al., Cancer Res. 61:3176 (2001)
down     Stanford Microarray - - Chen et al., Mol Biol Cell. 13:1929 (2002)
Links Entrez Gene    
Display nearby genome region Chr 11 from 52121603 bp to 62138902 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 297086 -- IMAGE clone locate on exon ( tblastx )
381066 -- IMAGE clone locate on exon ( tblastx )
756556 -- IMAGE clone locate on exon ( tblastx )
CH2 (-1.88) HK1 (-0.88) HK3 (-2.90) HK4 (1.43) HK5 (-0.33) HK7 (-0.27) HK9 (-0.53) HK11 (-0.86) HK12 (-0.55) HK13 (-0.06) HK14 (-2.27) HK15 (-0.62) HK16 (-9.03) HK18 (-0.64) HK19 (-0.27) HK20 (-1.30) HK21 (-0.90) HK22 (1.37) HK24 (0.04) HK27 (-2.25) HK28 (0.53) HK29 (0.32) HK31 (0.68) HK33 (-0.53) HK36 (0.34) HK37 (-1.96) HK38 (0.60) HK39 (-1.57) HK42 (-2.58) HK46 (-1.05) HK47 (-4.66) HK49 (0.64) HK62 (-0.09) HK63 (0.02) HK64 (-0.11) HK67 (-1.49) HK84 (0.42) HK85 (1.27) SF1 (0.23) SF12 (-1.34) SF15 (0.76) SF17 (1.36) SF18 (-0.53) SF21 (0.77) SF22 (2.80) SF23 (-0.28) SF32 (3.14) SF34 (0.80) SF35 (-1.07) SF3 (0.72) SF30 (0.15) HK2 (-2.93) HK23 (-1.43) HK41 (-0.18) SF4 (0.02) SF8 (0.31) SF9 (-1.04)