OncoDB.HCC Expression View

Gene name : MMP3
Ensembl ID ENSG00000149968
Description Stromelysin-1 precursor (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1) (SL-1). [Source:Uniprot/SWISSPROT;Acc:P08254]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
39 percent with 2 folds change ( 12 up and 6 down in 46 paired-arrays )
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- IHC, RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene    
Display nearby genome region Chr 11 from 97211738 bp to 107219552 bp

Standford microarray data
Re-analysis of Stanford microarray data
IMAGE clone 324492 -- IMAGE clone locate on exon ( tblastx )
CH2 (1.35) HK1 (0.00) HK3 (-0.23) HK4 (-1.20) HK5 (1.77) HK7 (0.00) HK9 (0.00) HK11 (4.94) HK12 (0.05) HK13 (0.00) HK14 (-1.22) HK15 (-0.22) HK16 (-1.62) HK18 (-0.20) HK19 (2.26) HK20 (-0.10) HK21 (0.11) HK22 (-0.04) HK24 (0.60) HK27 (1.10) HK28 (-0.43) HK29 (-1.56) HK31 (-0.41) HK33 (0.33) HK36 (1.46) HK37 (0.13) HK38 (-0.37) HK39 (0.66) HK42 (0.00) HK46 (0.34) HK47 (0.00) HK49 (0.00) HK62 (0.00) HK63 (0.00) HK64 (0.00) HK67 (1.14) HK84 (0.00) HK85 (0.00) SF1 (0.00) SF12 (0.00) SF15 (0.00) SF17 (0.00) SF18 (-1.61) SF21 (1.96) SF22 (0.00) SF23 (0.00) SF32 (0.13) SF34 (0.00) SF35 (0.00) SF3 (0.00) SF30 (2.26) HK2 (-1.72) HK23 (1.39) HK41 (0.00) SF4 (0.65) SF8 (1.90) SF9 (1.69)