OncoDB.HCC Expression View

Gene name : ADAM17
Ensembl ID ENSG00000151694
Description ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen). [Source:Uniprot/SWISSPROT;Acc:P78536]
HCC significant gene
Significantly up- or down- regulated in at least three independent HCC microarray/proteomic reports.
At least 2 folds expression change in more than 70% patients in reprocessed Stanford HCC microarray data.
With wet-lab experimental data from previous reports.
Experimental evidence up     Method -- RT-PCR    
>> Link to terminologies used in OncoDB.HCC
Links Entrez Gene     Entrez Gene    
Display nearby genome region Chr 2 from 4546066 bp to 14613368 bp